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About ANTcryo™
ANTcryo grids are Nickel Titanium(NiT) film on Au or Cu grids. Compared with carbon-film grids, they have much higher conductivity, resulting in a lower electron charging effect and less beam-induced motion (BIM) during cryoEM imaging. A higher-resolution structure can be then achieved. The products have been well adopted by the clients globally.
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Characteristics of ANTcryo™
Compared with carbon film, ANTcryo support film presents less nonspecific protein absorption, nearly 20 times lower, and therefore, improves particle distribution and reduces the aggregation of particles, leading to a higher success rate of sample preparation. Experimental images show more usable particles in the holes.
Citations
ANTcryo™ holey film sample supports have become recognized as the optimum choice to maximize reconstruction quality and resolution. As of December 2024, ANTcryo users have collectively published over 100 research articles, demonstrating a quality that exceeds the industry average.
1. Rosen A, et al. A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification. Cell. 2024;187(25):7196-7213.
2. Zheng L, et al. Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity. Cell Res. 2024;34(1):80-83.
3. Saito M, et al. Fanzor is a eukaryotic programmable RNA-guided endonuclease. Nature. 2023;620(7974):660-668.
4. Chen K, et al. Tail engagement of arrestin at the glucagon receptor. Nature. 2023;620(7975):904–910.
5. Lee B, et al. Structural basis of the activation of TRPV5 channels by long-chain acyl-coenzyme A. Nat Commun. 2023;14(1):5883.
Popular Models
grids type
錨點 1
M02-Cu300-1.2/1.3
Cu
300
1.2µm
1.3µm
50/box
M03-Au400-1.2/1.3
Au
400
1.2µm
1.3µm
50/box
M04-Au300-2.0/1.0
Au
300
2.0µm
1.0µm
50/box
Remark
Grid customization with variety of spec is possible. Contact for more info.
Film sickness 25 ± 3nm
Parameters
ANTcryo (Nickle- titanium alloy films)
Gold films
Carbon films
Film conductivity
Particle density in the hole
Mechanical strength
Coma free correction
Film thickness
22-28nm
40-50 nm
15-30 nm
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