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ANTcryo™ holy support film

It offers over 30 film geometries across various TEM grid materials and designs, ensuring high performance and flexibility to meet diverse cryo-EM research requirements.

About ANTcryo™

ANTcryo grids are Nickel Titanium(NiT) film on Au or Cu grids. Compared with carbon-film grids, they have much higher conductivity, resulting in a lower electron charging effect and less beam-induced motion (BIM) during cryoEM imaging. A higher-resolution structure can be then achieved. The products have been well adopted by the clients globally.  

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Characteristics of ANTcryo™   

Compared with carbon film, ANTcryo support film presents less nonspecific protein absorption, nearly 20 times lower, and therefore, improves particle distribution and reduces the aggregation of particles, leading to a higher success rate of sample preparation. Experimental images show more usable particles in the holes.

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Citations

ANTcryo™  holey film sample supports have become recognized as the optimum choice to maximize reconstruction quality and resolution. As of December 2023, ANTcryo users have collectively published over 60 research articles, demonstrating a quality that exceeds the industry average.   
Saito et al. Fanzor is a eukaryotic programmable RNA-guided endonuclease. Nat. 620, 660–668 (2023)
Lee et al. Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A. Nat. Commun. 14: 5883 (2023)
Zheng et al. Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity. Cell Res. 34: 80-83 (2024)
grids type

​Description

Material

Meshes

Hole size

Spacing

Unit

M01-Au300-1.2/1.3

Au

300

1.2µm

1.3µm

50/box

M02-Cu300-1.2/1.3

Cu

300

1.2µm

1.3µm

50/box

M03-Au400-1.2/1.3

Au

400

1.2µm

1.3µm

50/box

M04-Au300-2.0/1.0

Au

300

2.0µm

1.0µm

50/box

Remark

Grid customization with variety of spec is possible. Contact for more info.

Film sickness 22 ± 3nm

Parameters

ANTcryo (Nickle- titanium alloy films)

Gold films

Carbon films

Film conductivity

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Particle density in the hole

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Mechanical strength

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Coma free correction

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Film thickness

15-30 nm

40-50 nm

15-30 nm

*If you need to place an order, please send an email to this email address.*

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Need Assistance? We're here to help.

Unsure what to get? Have technical questions?
Contact SP and we'll help you design a custom system which will meet your research needs.

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