IT'S

TIME to superCHARGE

YOUR cryo-EM

workflow.

 
Still waiting for job execution on the shared cluster? How about YOUR OWN mini-cluster in a box? 

Cryo-electron microscopy (Cryo-EM) is an important research tool for structure biology and was chosen by Nature Methods as Methods of the Year 2015

To solve 3D structures of proteins and macromolecules, a suite of sophisticated cryo-EM image-processing software tools need to be used, such as RELION from MRC Laboratory of Molecular Biology. Many of the intrinsic image processing steps could be dramatically sped up by GPU parallelization. 

THE GPU revolution

With the introduction of GPU-accelerated RELION 2.0, the cryo-EM workflow can be significantly simplified. It is possible to achieve atomic resolution reconstruction on a single quad-GPU workstation within days and hours on a GPU cluster. 

Significant speed-up is seen when compared to a similarly priced CPU node in the 2D and 3D classification steps (ref. DOI: 10.1101/059717).

3D Classification

  Speedup: 40x

2D Classification

Speedup: 10x

 
 

OUR products

We offer GPU workstations as well as clusters optimized for cryo-EM workflow with a balance of performance and cost. 
  • Workstation Solutions Optimized for CryoEM
    Note that customization is fully supported but may increase build time.  

Intel i9

(8 to 18 cores)

64GB ECC DDR4
(up to 128GB)

2x NVIDIA RTX 2080Ti Graphics Cards with 11GB GDDR6

480GB Enterprise SSD

6TB Enterprise HDD

Recommended for developers and researchers with light load.

Mainstream

Workstation

Dual Intel Xeon Scalable

(8 cores at 2.10 GHz)

128GB ECC DDR4

(up to 1TB)

4x NVIDIA RTX 2080Ti Graphics Cards with 11GB GDDR6

512GB SSD for boot

2x 480GB Enterprise SSD

3x 6TB Enterprise HDD

Recommended for cryoEM researchers for routine use.

Dual Intel Xeon Scalable

(12 cores at 2.10 GHz)

256GB ECC DDR4

(up to 1TB)

4x NVIDIA RTX 2080Ti Graphics Cards with 11GB GDDR6

512GB SSD for boot

2x 480GB Enterprise SSD

6x 6TB Enterprise HDD

Recommended for power user working on large complexes.

Performance

Cluster Node

Dual Intel Xeon Scalable Gold

(14 cores)

256GB ECC DDR4

(up to 1TB)

4x GPUs in 1U
or 
8x or 10x GPUs in 4U

2x 480GB Enterprise SSD

Infiniband 56Gb

Optimized for rackmount applications. 

Developer

workstation

Performance

Workstation

  • Cluster Solutions Optimized for CryoEM
Computing

High GPU density

Easy cluster management with award-winning Bright Cluster Manager

Resource management with Slurm Workload Manager (multi-node RELION2 job submission with GPU support)

Storage

Expand capacity without downtime up to 300 PB (petabyte)

Low TCO (total cost of ownership)

High sustained throughput with HDDs only

Management

Flexibility to support mixed software versions

UNIQUE FEATURES

Enterprise quality

STABLE

Based on the cryo-EM use case, we optimize the build with enterprise quality parts, such as error-correcting code (ECC) memory and high-endurance Solid State Drives (SSDs). 

Optimized for RELION 2.0

PROVEN

We work closely with the RELION developers to ensure compatibility of our hardware and benchmark every system to spec before shipping.

Peace of mind

WORRY FREE

Every system passes strict factory burn-in and comes with 3 year hardware warranty bundled with free software updates and friendly support from our team of cryoEM experts

Ready to run

SIMPLE SETUP

Pre-installed with cryoEM data processing tools, such as RELION, as well as public tutorial datasets. This way you can quickly put it to work on your SHINY STRUCTURE!

Asia, Europe, US

GLOBAL YET LOCAL

Manufacturing facilities in US, China and Germany to meet quality standards

Save a tree

EFFICIENT

A single GPU workstation or GPU cluster node can replace multiple traditional CPU cluster nodes, saving space and energy!

 
Trusted by leading cryo-EM labs

 
ABOUT US
  • White Twitter Icon
  • White Facebook Icon

Single Particle, LLC is established to provide turn-key solutions and consulting for the growing cryo-EM community. Built by scientists with decades of combined experience in the field, Single Particle, LLC is striving to meet and exceed your expectations! 

 

We work closely with selected hardware vendors with facilities in the US, China and Germany. Let us build you the next-gen GPU workstation or cluster!

© 2017 by Single Particle, LLC

San Diego, California